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Oncolytic adenovirus
Adenovirus varieties have been explored extensively as a viral vector for gene therapy and also as an oncolytic virus.
Of the many different viruses being explored for oncolytic potential, an adenovirus was the first to be approved by a regulatory agency, the genetically modified H101 strain. It gained regulatory approval in 2005 from China's State Food and Drug Administration (SFDA) for the treatment of head and neck cancer.
==Engineering of oncolytic adenovirus==
Adenoviruses have so far been through three generations of development. Some of the strategies for modification of adenoviruses are described below.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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